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Filtered Search Results

Selleck Chemical LLC Ribociclib succinate S5188-25mg
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Ribociclib (LEE011) succinate is a highly specific dual inhibitor of CDK4 and CDK6 with IC50 of 10 nM and 39 nM respectively

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Selleck Chemical LLC Sumatriptan Succinate S1432-1g
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Sumatriptan Succinate (GR 43175) is a triptan sulfa drug containing a sulfonamide group for the treatment of migraine headaches

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Sigma Organic Chemistry tert-Butyl acetoacetate | 100ml | 1694-31-1 | MFCD00008811
tert-Butyl acetoacetate , 100ml
About this item:
CAS #: 1694-31-1
MDL #: MFCD00008811
Purity: ≥98
Molecular Weight: 158.19
UNSPSC Code: 12352100

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Sigma Organic Chemistry Cellulose Acetate Butyrate | 1EA
Cellulose Acetate Butyrate, 1EA
About This Item:
UNSPSC Code: 12352100
Storage: room temp

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Sigma Organic Chemistry Cellulose Acetate Butyrate | 5EA
Cellulose Acetate Butyrate, 5EA
About This Item:
UNSPSC Code: 12352100
Storage: room temp

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Sigma Organic Chemistry Cellulose Acetate Butyrate | 1EA
Cellulose Acetate Butyrate, 1EA
About This Item:
UNSPSC Code: 12352100
Storage: room temp

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Sigma Organic Chemistry Cellulose Acetate Butyrate | 5EA
Cellulose Acetate Butyrate, 5EA
About This Item:
UNSPSC Code: 12352100
Storage: room temp

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eMolecules Benzyl isovalerate | 103-38-8 | MFCD00048348 | 25g
Combi-Blocks, Inc. | Benzyl isovalerate | 25g | 603138663 | QF-8296 | 95.000 | 103-38-8 | MFCD00048348 | 192.258 | C12H16O2
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eMolecules Methyl oleate | 112-62-9 | MFCD00066521 | 10g
Oakwood Chemical | Methyl oleate | 10g | 537706960 | 098909 | | 112-62-9 | MFCD00066521 | 296.495 | C19H36O2
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Medchemexpress LLC HY-113144 5mg Medchemexpress, L-Hexanoylcarnitine CAS:22671-29-0 Purity:>98%
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Medchemexpress, HY-113144 5mg L-Hexanoylcarnitine CAS:22671-29-0 L-Hexanoylcarnitine is an acylcarnitine and is found to be associated with celiac disease. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.

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Sigma Organic Chemistry Dibutyl itaconate | 500ML | 2155-60-4 | MFCD00027211 | 0.96
Dibutyl itaconate, 500ML
About This Item:
Density: 0.985 g/mL at 25 C (lit.)
Refractive Index: n20/D 1.444 (lit.)
Storage: room temp
EINECS Number: 218-451-9

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Apexbio Technology LLC Solifenacin succinate 242478-38-2 100mg
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Solifenacin succinate (CAS 242478-38-2) is a selective muscarinic M3 receptor antagonist derived from tetrahydroisoquinoline and quinuclidine It primarily exerts its effect by competitively blocking acetylcholine binding at M3 receptors thereby attenuating muscarinic-mediated intracellular calcium mobilization In receptor binding assays solifenacin displays highest affinity for human M3 receptors (Ki 12 nM) It also selectively inhibits carbachol-induced contractions in isolated rat bladder tissues Consequently solifenacin succinate is frequently employed in biomedical research focused on lower urinary tract physiology and disorders associated with bladder hyperactivity

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Apexbio Technology LLC (±)-Octanoylcarnitine chloride 14919-35-8 25mg
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( )-Octanoylcarnitine chloride is an acyl derivative structurally related to acetylcarnitine chloride it functions as an intermediate in fatty acid metabolism by facilitating fatty acid transport across mitochondrial membranes for subsequent -oxidation and ATP synthesis Experimental evidence indicates that ( )-octanoylcarnitine modulates mitochondrial utilization of certain branched-chain 2-oxo acids influencing their oxidation rates in isolated mitochondria Additionally researchers employ ( )-octanoylcarnitine combined with malate to investigate mitochondrial respiratory activity examining oxidative phosphorylation dynamics in response to metabolic modulators such as ADP and creatine particularly in isolated cardiac muscle tissues

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Apexbio Technology LLC Solifenacin succinate 242478-38-2 50mg
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Solifenacin succinate (CAS 242478-38-2) is a selective muscarinic M3 receptor antagonist derived from tetrahydroisoquinoline and quinuclidine It primarily exerts its effect by competitively blocking acetylcholine binding at M3 receptors thereby attenuating muscarinic-mediated intracellular calcium mobilization In receptor binding assays solifenacin displays highest affinity for human M3 receptors (Ki 12 nM) It also selectively inhibits carbachol-induced contractions in isolated rat bladder tissues Consequently solifenacin succinate is frequently employed in biomedical research focused on lower urinary tract physiology and disorders associated with bladder hyperactivity

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Apexbio Technology LLC Monomethyl auristatin E 474645-27-7 5mg
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Monomethyl auristatin E (MMAE) is a highly potent antimitotic compound that exerts cytotoxic effects by inhibiting tubulin polymerization Microtubules play essential roles in various cellular processes including intracellular transport cell migration and mitotic chromosome segregation MMAE interrupts this process leading to cell cycle arrest and apoptosis MMAE is commonly utilized in preclinical and clinical studies as the cytotoxic payload in antibody-drug conjugates (ADCs) targeting tumor-specific antigens to selectively deliver cytotoxicity to cancer cells In vitro cell studies and in vivo tumor xenograft models show that antibody conjugation enables specific targeting resulting in reduced off-target toxicity and improved therapeutic index compared to unconjugated cytotoxic agents

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